What does this research mean for the field?

Endoscopic transorbital approaches are a safe, effective, and function-preserving alternative to traditional microsurgical transcranial approaches for selected intraparenchymal temporal lesions, achieving high resection rates with minimal visual field deterioration or complications. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To assess the safety, surgical efficacy, and technical nuances of endoscopic transorbital approaches for accessing intraparenchymal temporal brain lesions.

August 27, 2026Neurosurgical ReviewOpen Access

Navigare necesse est: The transorbital route to intraparenchymal temporal lesions

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Authors

EAEdoardo AgostiSurgical Specialties (Canada)LGLorenzo GelminiUniversity of Brescia FCFrancesco CorrivettiEuropean Biomedical Research Institute of Salerno

Discussion

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Implication

Systematic review demonstrates high resection rates and vision preservation in temporal lesion surgery, highlighting transorbital endoscopy as a safe corridor.

Key Points

To assess the safety, surgical efficacy, and technical nuances of endoscopic transorbital approaches for accessing intraparenchymal temporal brain lesions.
Conducted a PRISMA-compliant systematic review searching PubMed, Scopus, and Ovid MEDLINE.
Synthesized data from 13 studies involving 41 patients with intraparenchymal lesions in the mediobasal temporal region (87.8%) and temporal pole (12.2%).
Gross total resection was achieved in 73.0% (n=27), subtotal resection in 13.5% (n=5), partial resection in 8.1% (n=3), and biopsy in 5.4% (n=2).
No patients experienced postoperative visual field deterioration, with 79.3% (23/29) retaining intact preoperative visual fields.
Postoperative complications included a single cerebrospinal fluid leak (2.6%) and no permanent cranial nerve deficits.

Cite This Study

Agosti et al. (2026) studied this question.

synapsesocial.com/papers/6a8fea3310c91c1e92622449 https://doi.org/10.1007/s10143-026-04402-x

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Implication

Systematic review demonstrates high resection rates and vision preservation in temporal lesion surgery, highlighting transorbital endoscopy as a safe corridor.

Navigare necesse est: The transorbital route to intraparenchymal temporal lesions

Discussion

Member takes

Implication

Key Points

Cite This Study

Navigare necesse est: The transorbital route to intraparenchymal temporal lesions

Discussion

Member takes

Implication

Key Points

Cite This Study

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