What question did this study set out to answer?

Evaluate the diagnostic and therapeutic efficacy of pericardial biopsy in patients presenting with complex pericarditis and pericardial effusion.

May 19, 1956JAMA

Diagnosis and Treatment of Cardiac Pericarditis by Pericardial Biopsy

View Full Paper

Ask AI

Bookmark

Why the study?

Is pericardial biopsy safe and effective for the diagnosis and treatment of cardiac pericarditis?

Population

16 patients with cardiac pericarditis, including 6 with hemorrhagic pericarditis and 1 with tuberculous…

Design

Case_series

Authors

WPWilliam L. ProudfitCleveland Clinic

Discussion

Member takes

Implication

Pericardial biopsy may enable safe direct access in tamponade; hypothesis-generating and should not yet change practice.

Key Points

Evaluate the diagnostic and therapeutic efficacy of pericardial biopsy in patients presenting with complex pericarditis and pericardial effusion.
Conducted pericardial biopsies in N=16 patients, including 6 with hemorrhagic pericarditis and 1 with tuberculous pericarditis.
Used the surgical approach to enable direct inspection of the pericardial space, fluid and tissue cultures, and effusion drainage into the left pleural cavity.
Biopsy enabled direct visualization of the pericardial sac and provided tissue and fluid samples for microbiological culture across all 16 patients.
Abrupt fluid decompression in patients with cardiac tamponade produced no adverse events, and postoperative reactions were mild.

Structured PICO

Is pericardial biopsy safe and effective for the diagnosis and treatment of cardiac pericarditis?

Population

16 patients with cardiac pericarditis, including 6 with hemorrhagic pericarditis and 1 with tuberculous pericarditis

Intervention

Pericardial biopsy (permitting direct inspection, culture of fluid and tissue, and drainage into the left pleural cavity)

Outcome

Diagnostic utility and procedural safety/postoperative reactionssafety

Pericardial biopsy is a safe and useful procedure for the diagnosis and management of cardiac pericarditis, allowing for fluid drainage and tissue culture without severe postoperative reactions.

Cite This Study

William L. Proudfit (1956) studied this question.

synapsesocial.com/papers/6a90110002529ca22a277fbf https://doi.org/10.1001/jama.1956.02970030006002

Topics

Pericardial disease

View Full Paper

Ask AI

Bookmark

Diagnosis and Treatment of Cardiac Pericarditis by Pericardial Biopsy

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Diagnosis and Treatment of Cardiac Pericarditis by Pericardial Biopsy

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider