Why the study?
Does thoracoscopic pericardial fenestration improve diagnostic yield and reduce recurrence in patients with pericardial effusion?
Does thoracoscopic pericardial fenestration improve diagnostic yield and reduce recurrence in patients with pericardial effusion?
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Thoracoscopic pericardial fenestration is highly effective for diagnosing the aetiology of pericardial effusions, and adding bleomycin sclerosis reduces recurrence in malignant cases.
The cause of cardiac tamponade is only established in 50% of cases. This problem is most commonly treated by pericardiocentesis alone, pericardiotomy being reserved for cases of recurrence and pericardiectomy for those patients presenting with constrictive pericarditis. A series of 16 patients treated with pericardial fenestration via a thoracoscope is presented. Pericardial and pleural biopsies were performed, together with cytological and biochemical analysis of the pericardial and pleural fluid where present. This procedure established the aetiology of effusion in all cases. In malignant pericardial effusion bleomycin was used for pericardial sclerosis. This resulted in fewer recurrences than in those patients where sclerosis was not attempted (12.5% v 60%).
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Cantó et al. (1993) studied this question.
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