Key result
Viral pathogens were detected in 66.57% of children with LRTIs and 47.10% of children with URTIs, with differing viral spectrums and coinfection rates.
Cross-Sectional (n=720)
The spectrum of respiratory virus infections in children with URTIs and LRTIs differs significantly in terms of the most common pathogens and coinfection rates.
The viral etiologies of UTRIs and LTRIs in children in Jinan city were investigated between July 2009 and June 2010. Nasal and throat swabs were collected from 397 children with URTIs and bronchoalveolar lavage fluid specimens were collected from 323 children with LRTIs. RT-PCR/PCR was used to examine all samples for IFV, PIV, RSV, RV, hMPV, HBoV, CoV, ADV, RSV, and EV. Viral pathogens were detected in 47.10% of URTI samples and 66.57% samples, and the incidence of viral coinfection was 5.29% and 21.05%, respectively. IFV was the most common virus in URTIs, with a detection rate of 19.40%, followed by PIV (10.83%), RV (10.58%), and EV (6.30%). For LRTIs, PIV and RV were both detected in 27% of samples, followed by RSV (9.91%), HBoV (8.36%), IFV (5.57%), and hMPV (5.57%). RSV and HBoV were more prevalent in the youngest children of no more than six months. Meanwhile, RV, PIV, and RSV were the most frequent viruses combined with bacterial pathogens in LRTIs. In conclusion, the spectrum of respiratory virus infections in URTIs and LRTIs differed in terms of the most common pathogens, seasonal distribution, and coinfection rate.
No takes yet. Share an insight, caveat, or question.
Lu et al. (2013) conducted a cross-sectional in Acute Respiratory Tract Infections (n=720). Lower respiratory tract infections (LRTIs) vs. Upper respiratory tract infections (URTIs) was evaluated on Detection of viral pathogens. Viral pathogens were detected in 66.57% of children with LRTIs and 47.10% of children with URTIs, with differing viral spectrums and coinfection rates.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: