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Article1 May 1964The Association of Chronic "Nonspecific" Inflammatory Bowel Disease with Lupus ErythematosusDONALD J. KURLANDER, M.D., JOSEPH B. KIRSNER, M.D., PH.D.DONALD J. KURLANDER, M.D., JOSEPH B. KIRSNER, M.D., PH.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-60-5-799 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptGastrointestinal manifestations in patients with lupus erythematosus are common and may include dysphagia, anorexia, nausea, vomiting, diarrhea, hemorrhage, and abdominal pain of varying severity (1). Abdominal distress in this disease has been associated with peritonitis, ileus, perihepatitis, perisplenitis, "lupoid hepatitis," pancreatitis, and intestinal ulceration or perforation (2-4). The association of ulcerative colitis or regional enteritis with discoid or systemic lupus erythematosus, or both, has been noted infrequently (2, 5, 7). Five such patients currently are under observation at the University of Chicago and are described in this paper.CASE REPORTSCASE 1. DISCOID AND POSSIBLY SYSTEMIC LUPUS ERYTHEMATOSUS WITH PROBABLE...References1. HARVEYSHULMANTUMULTYCONLEYSCHOENRICH AMLDPACLEH: Systemic lupus erythematosus: review of the literature and clinical analysis of 138 cases. Medicine 33: 291, 1954. CrossrefMedlineGoogle Scholar2. BROWNSHIREYHASERICK CEJ: Gastrointestinal manifestations of systemic lupus erythematosus. Gastroenterology 31: 649, 1956. CrossrefMedlineGoogle Scholar3. FINKBINERDECKER RBJP: Ulceration and perforation of the intestine due to necrotizing arteriolitis. New Eng. J. Med. 268: 14, 1963. CrossrefGoogle Scholar4. BERGPOSTELLEE PAS: Perforation of the ileum in steroid-treated systemic lupus erythematosus. Amer. J. Dig. Dis. 5: 274, 1960. CrossrefMedlineGoogle Scholar5. BROWNHASERICKSHIREY CJE: Chronic ulcerative colitis with systemic lupus erythematosus. Cleveland Clin. Quart. 23: 43, 1956. 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POLLAKGROVEKARKMUEHRCKEPIRANISTECK VEWJRMRCCLLE: Systemic lupus erythematosus simulating acute surgical condition of the abdomen. New Eng. J. Med. 259: 258, 1958. CrossrefMedlineGoogle Scholar25. BRUCESIRCUS JW: Disseminated lupus erythematosus of the alimentary tract. Lancet 1: 795, 1959. CrossrefMedlineGoogle Scholar26. KIRSNER JB: Ulcerative colitis: certain clinical aspects and problems. Gastroenterology 40: 287, 1961. CrossrefMedlineGoogle Scholar27. LEVINEKIRSNERKLOTZ MDJBAP: A new concept of the pathogenesis of ulcerative colitis. Science 114: 552, 1951. CrossrefMedlineGoogle Scholar28. JACOBSONKIRSNER MJB: The basement membranes of the epithelium of the colon and rectum in ulcerative colitis and other diseases. Gastroenterology 30: 279, 1956. CrossrefMedlineGoogle Scholar29. HOLMAN H: The L. E. cell phenomenon. Ann. Rev. Med. 11: 231, 1960. CrossrefMedlineGoogle Scholar30. KIRSNER JB: Immunologic considerations in ulcerative colitis. Surg. Clin. N. Amer. 42: 1115, 1962. CrossrefMedlineGoogle Scholar31. KRAFTBREGMANKIRSNER SEJB: Criteria for evaluating autoimmune phenomena in ulcerative colitis. Gastroenterology 43: 330, 1962. CrossrefMedlineGoogle Scholar32. WARRENSOMMERS SS: Pathogenesis of ulcerative colitis. Amer. J. Path. 25: 657, 1949. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: DONALD J. KURLANDER, M.D.; JOSEPH B. KIRSNER, M.D., PH.D.Affiliations: Chicago, IllinoisFrom the Department of Medicine, University of Chicago, Chicago, Illinois.This study was supported in part by grant CA-09467 from the National Institute of Arthritis and Metabolic Diseases, National Institutes of Health, United States Public Health Service, Bethesda, Maryland.Requests for reprints should be addressed to Joseph B. Kirsner, M.D., Ph.D., Department of Medicine, University of Chicago, 950 E. 59th Street, Chicago, Illinois 60637. 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CHRISTOPHER, M.D., DAVID W. WATSON, M.D., F.A.C.P., EDWARD R. FARBER, M.D.A Syndrome Resembling Relapsing Polychondritis In A Patient With Ulcerative Colitis50. Entzündliche Erkrankungen des DickdarmesRecent Advances in the Rheumatic DiseasesEPHRAIM P. ENGLEMAN, M.D., F.A.C.P., MARTIN A. SHEARN, M.D., F.A.C.P.Immunological Mechanisms of the Gastrointestinal TractA survey of vascular diseases of the small intestineEntero-arthropathy: The Coexistence of Articular and Gastrointestinal Manifestations in Systemic DiseaseAuto-immune reactions in ulcerative colitis.Ulcerative Colitis and SclerodermaUlcerative Colitis: A Report of Progress, Based Upon the Recent Literature 1 May 1964Volume 60, Issue 5Page: 799-813KeywordsColitisLupus erythematosusMetabolic disordersNauseaPancreatitisPeritonitisPrevention, policy, and public healthUlcerative colitisUlcersVomiting ePublished: 1 December 2008 Issue Published: 1 May 1964 PDF downloadLoading ...
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Donald J. Kurlander (1964) studied this question.
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