What question did this study set out to answer?

To compare the prevalence and spectrum of psychiatric disorders between adults with Down's syndrome and matched adults with intellectual disabilities from other causes.

November 1, 1992The British Journal of Psychiatry

Differential Rates of Psychiatric Disorders in Adults with Down's Syndrome Compared with Other Mentally Handicapped Adults

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Authors

RCR. A. CollacottRoyal Society of Medicine SCSally‐Ann CooperUniversity of Glasgow CMCatherine W. McGrotherUniversity of Leicester

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Implication

Matched comparative study reveals distinct psychiatric profiles in adults with Down's syndrome, indicating heightened susceptibility to depression and dementia.

Key Points

To compare the prevalence and spectrum of psychiatric disorders between adults with Down's syndrome and matched adults with intellectual disabilities from other causes.
Ascertained 378 adults with Down's syndrome across Leicestershire through comprehensive survey.
Matched 371 individuals with Down's syndrome to 371 control adults with intellectual disabilities of other etiologies based on age, sex, and residence type.
Adults with Down's syndrome had higher diagnostic rates of depression and dementia compared with matched controls.
Controls were more frequently diagnosed with conduct disorder, personality disorder, and schizophrenia or paranoid states.
Autism diagnoses occurred in equal proportions between both cohorts.

Cite This Study

Collacott et al. (1992) studied this question.

synapsesocial.com/papers/6a90136af009383eee84060d https://doi.org/10.1192/bjp.161.5.671

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Implication

Matched comparative study reveals distinct psychiatric profiles in adults with Down's syndrome, indicating heightened susceptibility to depression and dementia.

Differential Rates of Psychiatric Disorders in Adults with Down's Syndrome Compared with Other Mentally Handicapped Adults

Discussion

Member takes

Implication

Key Points

Cite This Study

Differential Rates of Psychiatric Disorders in Adults with Down's Syndrome Compared with Other Mentally Handicapped Adults

Discussion

Member takes

Implication

Key Points

Cite This Study

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