Why the study?
Does decreased hormone replacement therapy use reduce acute stroke and myocardial infarction event rates in women aged 40 to 79 years?
Does decreased hormone replacement therapy use reduce acute stroke and myocardial infarction event rates in women aged 40 to 79 years?
The population-wide decline in HRT use after 2002 was associated with a significant decrease in acute myocardial infarction rates among US women, supporting the findings of the Women's Health Initiative.
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Observed MI reduction after population HRT decline should not change practice; leaves open causal confirmation and stroke effects in prospective data.
Shetty et al. (2009) studied this question.
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