Key result
Incomplete Kawasaki disease is linked to ~3-fold higher coronary artery involvement vs complete disease.
Why the study?
Kawasaki disease is a common childhood vasculitis with variable clinical presentations and cardiovascular complications requiring evaluation over time.
Does the rate of coronary artery involvement and clinical presentation differ between children with incomplete versus complete Kawasaki disease?
Observational (n=39)
No
Does the rate of coronary artery involvement and clinical presentation differ between children with incomplete versus complete Kawasaki disease?
Children with incomplete Kawasaki disease presented with a significantly higher rate of coronary artery involvement than those with classic complete Kawasaki disease, emphasizing the need for early echocardiography in suspected cases.
Answers are grounded in this paper and cite their sources.
Supports heightened vigilance for coronary complications in incomplete Kawasaki disease; leaves open whether prospective studies should revise diagnostic thresholds.
Objective: Kawasaki disease is one of the most common childhood forms of vasculitis.The aim of this study was to evaluate children with Kawasaki disease hospitalized in our pediatrics department over a 6-year period.Methods: A total of 39 children treated for Kawasaki disease in the pediatric department between January 2008 and December 2013 were evaluated retrospectively.Results: Of 39 patients, 29 (74.3%) were male and 10 (25.6%) were female.The male/ female ratio was 2.9.The mean patient age was 31.82±20.31months.In all, 2 patients were diagnosed with Kawasaki disease in 2008, 6 in 2009, 5 in 2010, 7 in 2011, 10 in 2012 and 9 in 2013.Lesions of the oral cavity were found in 89.7%, extremity changes were observed in 61.5%, conjunctivitis was seen in 76.9%, polymorphous exanthema was detected in 74.4%, and lymphadenopathy was present in 61.5% of the patients.In 22 patients, coronary artery disease was detected on an echocardiogram.According to the Kawasaki disease diagnostic criteria, 64.1% were diagnosed as complete Kawasaki disease and 35.9% as incomplete.Myocardial infarction or death did not occur. Conclusion:The cardiovascular complications of Kawasaki disease can be prevented with early diagnosis and treatment in both complete and incomplete cases.
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Mehmet Gündüz (2018) conducted an observational in Kawasaki disease (n=39). Incomplete Kawasaki disease vs. Complete Kawasaki disease was evaluated on Coronary artery involvement (p=0.001). Coronary artery involvement on echocardiogram was higher in patients with incomplete Kawasaki disease compared to those with complete Kawasaki disease.
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