Key result
Neutrophil-to-lymphocyte ratio significantly increased 24 hours after femur intramedullary fixation for hip fracture, but showed no significant effect on length of hospital stay.
Why the study?
Use of the neutrophil-to-lymphocyte ratio is spreading as a predictor of postoperative outcome in orthopaedic surgery, prompting investigation into its change 24 hours after surgical intervention.
Does femur intramedullary fixation affect the Neutrophil-to-lymphocyte ratio (NLR) 24 hours post-surgery in elderly patients with hip fracture?
Cohort (n=91)
Does femur intramedullary fixation affect the Neutrophil-to-lymphocyte ratio (NLR) 24 hours post-surgery in elderly patients with hip fracture?
NLR significantly increases 24 hours after femur intramedullary fixation for hip fracture in elderly patients, but does not predict length of hospital stay.
No immediate clinical role for NLR in discharge decisions; leaves open its prognostic value in hip fracture research.
Neutrophil-to-lymphocyte ratio (NLR) was developed as a diagnostic and prognostic tool in many medical conditions, and its use is spreading as a predictor of postoperative outcome in orthopaedic surgery. The aim of this study is to investigate the improvement of NLR 24 hours after surgical intervention in a cohort of 91 patients (F/M = 68/23) with hip fracture who underwent femur intramedullary fixation. Patients were 84.7 ± 7.9 years old, and the mean hospital stay was 13.4 ± 4.7 days, with a mean delay to surgery of 1.9 ± 1.4 days. A significant increase in NLR between baseline (T0) and 24 hours after surgical intervention (T1) was observed in the study sample overall and on subgroup analysis by gender. Nevertheless, no significant effect of NLR on the length of hospital stay was observed.
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Tomaino et al. (2022) conducted a cohort in hip fracture (n=91). Neutrophil-to-lymphocyte ratio (NLR) was evaluated on Change in NLR 24 hours after surgical intervention and effect on length of hospital stay. Neutrophil-to-lymphocyte ratio significantly increased 24 hours after femur intramedullary fixation for hip fracture, but showed no significant effect on length of hospital stay.
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