In 1186 patients with systemic malignant B-cell lymphomas, the skin was involved in 6.17% of low-grade malignant, 9.7% of medium-grade malignant, and 7.4% of high-grade malignant lymphomas. Skin involvement is associated with an impaired prognosis in malignant B-cell lymphomas, with the exception of medium-grade malignant lymphomas.
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Sterry et al. (1984) studied this question.
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