Why the study?
Does a novel pulsatile augmentation device provide acceptable blood compatibility and hemodynamic function in extracorporeal bypass circuits?
Population
In vitro model using fresh bovine blood and in vivo right and left heart extracorporeal bypass circuit model
Design
Preclinical
Follow-up
4 h (in vivo testing)
Authors
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Should not yet change bypass practices; hypothesis-generating for pulsatile devices pending longer validation.
Does a novel pulsatile augmentation device provide acceptable blood compatibility and hemodynamic function in extracorporeal bypass circuits?
A novel valveless, pneumatically driven pulsatile augmentation device shows promise for adding pulsatile flow to standard cardiopulmonary bypass and right heart circulatory assist circuits.
Doty et al. (1996) studied this question.
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