Key result
Pulsatile blood flow during proximal graft significantly reduced the need for inotrope support during weaning from cardiopulmonary bypass compared to non-pulsatile flow.
Why the study?
Even short-term pulsatile flow can decrease the need for inotrope support and facilitate weaning from CPB, prompting investigation of pulsatile flow during proximal graft in CABG surgery.
Does pulsatile blood flow during proximal graft reduce the need for inotrope support in patients undergoing CABG surgery?
RCT (n=74)
randomly divided
Does pulsatile blood flow during proximal graft reduce the need for inotrope support in patients undergoing CABG surgery?
Inducing pulsatile blood flow during proximal grafting in CABG surgery may facilitate weaning from cardiopulmonary bypass by reducing the need for inotropic support.
BACKGROUND: Even short time pulsatile flow can decrease the need for inotrope support and facilitate weaning from cardiopulmonary bypass. Thus clinical study was designed to investigate the effect of pulsatile flow during proximal graft in order to reduce the need for inotrope support during weaning from cardiopulmonary bypass (CPB) pump in coronary artery bypass graft (CABG) surgery.METHODS: In this randomized clinical trial study 74 patients who underwent CABG surgery were randomly divided into two groups of a) pulsatile flow and b) non-pulsatile flow. Continuous blood flow was transferred to pulsatile blood flow during proximal graft by using cardiac contraction.RESULTS: Our results clearly showed that using pulsatile flow significantly reduces the need for inotrope support.CONCLUSIONS: It is suggested that pulsatile flow be induced by use of cardiac contraction during proximal graft in CABG surgery in the same way as our method which is mentioned in the body of the paper.
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Amouzegarzavareh et al. (2020) conducted an RCT in Coronary artery bypass graft (CABG) surgery (n=74). Pulsatile blood flow during proximal graft vs. Non-pulsatile flow was evaluated on Need for inotrope support during weaning from cardiopulmonary bypass. Pulsatile blood flow during proximal graft significantly reduced the need for inotrope support during weaning from cardiopulmonary bypass compared to non-pulsatile flow.
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