Key result
Older age (≥65 years) was associated with a higher arterial to end-tidal partial pressure gradient of carbon dioxide during general anesthesia compared to age 16 to <65 years (4.1 vs 3.0 mmHg).
Why the study?
Does the arterial to end-tidal partial pressure gradient of carbon dioxide vary by age during general anesthesia in the supine position?
Population
596 patients aged ≥16 years who underwent general anesthesia in the supine position.
Design
Cohort
Follow-up
intraoperative
Authors
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May influence capnography interpretation in elderly patients under anesthesia; hypothesis-generating and requires prospective validation.
Observational (n=596)
Does the arterial to end-tidal partial pressure gradient of carbon dioxide vary by age during general anesthesia in the supine position?
Absolute Event Rate: 4.1% vs 3%
The arterial to end-tidal partial pressure gradient of carbon dioxide increases with age during general anesthesia in the supine position.
Satoh et al. (2015) conducted an observational in General anesthesia in the supine position (n=596). Age ≥65 years vs. Age 16 to <65 years was evaluated on Arterial to end-tidal partial pressure gradient of carbon dioxide (a-ETCO2). Older age (≥65 years) was associated with a higher arterial to end-tidal partial pressure gradient of carbon dioxide during general anesthesia compared to age 16 to <65 years (4.1 vs 3.0 mmHg).
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