Key result
Wavelet transformed signal averaged electrocardiogram combined with a probabilistic neural network detected acute myocardial infarction with 93.0% sensitivity, 86.0% specificity, and 89.5% accuracy.
Why the study?
Does SAECG with wavelet transform and probabilistic neural network accurately detect acute myocardial infarction compared to healthy subjects?
Case-Control (n=100)
Does SAECG with wavelet transform and probabilistic neural network accurately detect acute myocardial infarction compared to healthy subjects?
Effect estimate: 89.5% accuracy
Absolute Event Rate: 93% vs 86%
SAECG combined with wavelet transform and probabilistic neural networks shows high accuracy in discriminating acute myocardial infarction patients from healthy subjects.
Should not yet change AMI diagnostic practice; leaves open prospective validation of wavelet SAECG with neural networks.
There are a variety of electrocardiogram based methods to detect myocardial infarction (MI) patients. This study used the signal averaged electrocardiogram (SAECG) and its wavelet coefficient as an index to detect MI. Orthogonal leads signals from 50 acute myocardial infarction (AMI) and 50 healthy subjects were selected from the national metrology institute of Germany (PTB diagnostic database). They were filtered and discrete wavelet transformed was exerted on them. Four conventional features and two new features introduced in this study were extracted from SAECG and its wavelet decompositions. Finally for data classification, probabilistic neural network were used. This method was able to detect and discriminate AMI patients from healthy subjects using the probabilistic neural network, which shows 93.0% sensitivity at 86.0% specificity with 89.5% accuracy. This technique and the new extracted features showed good promise in the identification of MI patients. However, the sensitivity and specificity is comparable with other findings and has high accuracy although we extracted only 6 features.
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Keshtkar et al. (2013) conducted a case-control in Acute Myocardial Infarction (n=100). Wavelet transformed signal averaged electrocardiogram (WTSAECG) and probabilistic neural network vs. Healthy controls was evaluated on Diagnostic accuracy (sensitivity and specificity) for detecting acute myocardial infarction (89.5% accuracy). Wavelet transformed signal averaged electrocardiogram combined with a probabilistic neural network detected acute myocardial infarction with 93.0% sensitivity, 86.0% specificity, and 89.5% accuracy.
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