Key result
This review analyzes the current literature on the use of sugammadex for the reversal of neuromuscular blockade in older adults, highlighting the impact of aging on its pharmacokinetics.
Why the study?
Does sugammadex safely and effectively reverse neuromuscular blockade in elderly patients?
Population
Elderly patients requiring reversal of neuromuscular blockade
Design
Review
Authors
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May require age-adjusted sugammadex dosing in older adults; leaves open need for dedicated geriatric trials.
Does sugammadex safely and effectively reverse neuromuscular blockade in elderly patients?
This review highlights the need to consider age-related pharmacokinetic changes when using sugammadex for neuromuscular blockade reversal in elderly patients.
Carron et al. (2017) conducted a review in Neuromuscular blockade in elderly patients. Sugammadex was evaluated. This review analyzes the current literature on the use of sugammadex for the reversal of neuromuscular blockade in older adults, highlighting the impact of aging on its pharmacokinetics.
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