Key result
Sugammadex administration triggered severe dysrhythmia and repetitive cardiac arrest in a 76-year-old man who was subsequently diagnosed with variant angina.
Case Report (n=1)
No
Sugammadex administration may trigger severe coronary vasospasm and cardiac arrest in patients with underlying variant angina.
Alerts clinicians to potential sugammadex-induced spasm in variant angina; single case leaves open causality and needs confirmation.
A 76-year-old man with no notable medical history was scheduled for a robot-assisted radical prostatectomy. After the operation, he was given sugammadex. Two minutes later, ventricular premature contraction bigeminy began, followed by cardiac arrest. Cardiac arrest occurred three times and cardiopulmonary resuscitation was done. The patient recovered after the third cardiopulmonary resuscitation and was transferred to the intensive care unit. Coronary angiography was done on postoperative day 1. The patient was diagnosed with variant angina and discharged uneventfully on postoperative day 8.
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Ko et al. (2016) conducted a case report in Variant angina (n=1). Sugammadex was evaluated on Cardiac arrest. Sugammadex administration triggered severe dysrhythmia and repetitive cardiac arrest in a 76-year-old man who was subsequently diagnosed with variant angina.
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