Key result
Direct oral anticoagulants, specifically Factor Xa inhibitors, offer a strategy for venous thromboembolism prevention in the extended post-hospital period for patients with acute medical problems.
Why the study?
Do Factor Xa inhibitors prevent venous thromboembolism in the extended post-hospital period for patients with acute medical problems?
Do Factor Xa inhibitors prevent venous thromboembolism in the extended post-hospital period for patients with acute medical problems?
This review highlights the underreported risk of VTE up to 3 months post-hospitalization and discusses the role of Factor Xa inhibitors for extended VTE prophylaxis.
May support extended VTE prophylaxis with Factor Xa inhibitors after medical hospitalization; leaves open need for confirmatory RCTs.
The risk of a venous thromboembolic event is not limited to the pre-hospital, hospital, or immediate post-hospital period. Because of challenges with data collection, the risk of venous thromboembolism (VTE) up to 3 months post-hospitalization for patients with acute and serious medical problems in the setting of chronic disease and/or risk factors for VTE is probably under reported. The growing acceptance and indications of direct oral anticoagulants (DOACs) now includes an indication for VTE prevention for one of the Factor Xa agents. In this paper, the authors explore the issue of VTE in the extended post-hospital period and strategies to provide protection from these morbid and potentially mortal events with oral anticoagulants.
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Al‐Hillan et al. (2018) conducted a review in Venous thromboembolism. Factor Xa inhibitors was evaluated. Direct oral anticoagulants, specifically Factor Xa inhibitors, offer a strategy for venous thromboembolism prevention in the extended post-hospital period for patients with acute medical problems.
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