Key result
Single-stage hybrid atrial fibrillation ablation achieved a 76% success rate in maintaining sinus rhythm off antiarrhythmic drugs at 1 year in patients with persistent AF or failed catheter ablation.
Why the study?
Hybrid thoracoscopic and percutaneous AF ablation treats therapy-resistant symptomatic AF, but its efficacy, safety, determinants of success, and quality-of-life impact in symptomatic persistent AF or failed endocardial ablation required evaluation.
Does single-stage hybrid AF ablation improve sinus rhythm maintenance in patients with persistent AF or failed catheter ablation?
Observational (n=50)
No
Does single-stage hybrid AF ablation improve sinus rhythm maintenance in patients with persistent AF or failed catheter ablation?
Single-stage hybrid AF ablation is effective in maintaining sinus rhythm off antiarrhythmic drugs in 76% of patients with persistent or therapy-resistant AF at 1 year, though it carries a 14% complication rate.
No takes yet. Share an insight, caveat, or question.
May support hybrid ablation in persistent AF; hypothesis-generating and requires randomized confirmation before practice change.
Al-Jazairi et al. (2019) conducted an observational in Atrial fibrillation (persistent, long-standing persistent, or paroxysmal with failed catheter ablation) (n=50). Single-stage hybrid atrial fibrillation ablation was evaluated on First AF/AFL/AT recurrence documented by ECG, Holter monitoring (>30 s), or event recorder during 12-month follow-up (excluding 90-day blanking period). Single-stage hybrid atrial fibrillation ablation achieved a 76% success rate in maintaining sinus rhythm off antiarrhythmic drugs at 1 year in patients with persistent AF or failed catheter ablation.
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