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August 3, 2023Open Access

Incidence and factors associated with failed spinal anaesthesia among patients undergoing surgery: A multi- center prospective observational study

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Key result

The overall incidence of failed spinal anaesthesia was 22.4% among patients undergoing surgery, with emergency surgery, low bupivacaine dose, and inexperienced anaesthetists identified as significant risk factors.

Why the study?

The study was conducted to determine the incidence and factors associated with failed spinal anaesthesia among patients undergoing surgery in Amhara National Regional State comprehensive specialized hospitals.

Population

532 patients undergoing surgery in Amhara National Regional State comprehensive specialized hospitals

Design

Multi-center prospective observational study

Authors

ADAtalay Eshetie DemilieBahir Dar UniversityZDZewditu Abdissa DenuUniversity of GondarYBYosef Belay BizunehUniversity of Gondar

Discussion

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Overview

High failure incidence signals need for technique optimization in similar settings; leaves open whether interventions targeting identified factors reduce rates.

Study Design

Type

Observational (n=532)

Multicenter

Yes

Structured PICO

P
Population
532 patients undergoing surgery under spinal anaesthesia at three comprehensive specialized hospitals in Northwest Ethiopia.
E
Exposure
Spinal anaesthesia using bupivacaine (various doses, baricities, and adjuvants)
O
Outcome
Failed spinal anaesthesia (partial or incomplete spinal block within 15-20 minutes after injection requiring supplemental analgesia or conversion to general anaesthesia)

Failed spinal anaesthesia occurs in over 20% of cases in this Ethiopian setting, strongly associated with emergency surgery, bloody CSF, low bupivacaine dose, and lack of adjuvants.

Cite This Study

Demilie et al. (2023) conducted an observational in Patients undergoing surgery under spinal anaesthesia (n=532). Risk factors for failed spinal anaesthesia was evaluated on Incidence of failed spinal anaesthesia (95% CI 19.0-25.9). The overall incidence of failed spinal anaesthesia was 22.4% among patients undergoing surgery, with emergency surgery, low bupivacaine dose, and inexperienced anaesthetists identified as significant risk factors.

synapsesocial.com/papers/6a902cfc028f4c29a42b1d6ahttps://doi.org/10.21203/rs.3.rs-3177596/v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Incidence and Causes of Failed Spinal Anesthetics in a University Hospital: A Prospective Study1991 · 43 citations
  2. 2Litigation related to regional anaesthesia: an analysis of claims against the NHS in England 1995–2007*2010 · 78 citations
  3. 3Spinal blocks2011 · 97 citations
  4. 4Effect of regional versus general anaesthesia on postoperative delirium in elderly patients undergoing surgery for hip fracture: a systematic review2018 · 125 citations
  5. 5Spinal Process Landmark as a Predicting Factor for Difficult Epidural Block: A Prospective Study in Taiwanese Patients2003 · 26 citations