On Estimating the Constants of the `Multi-Hit' Curve Using a Medium Speed Digital Computer

A 1-pass computer programme in Fortran is presented that produces least squares estimates and standard errors for the constants of the `Multi-Hit' curve. The mathematical expression for the curve is S =1−[1−exp(− kD )] n where S is the proportional response to a dose D , and k and n are constants to be estimated. The programme permits the choice of 3 weighting factors and accepts data entered as individual values or as means with associated weights.