Experimental study reveals a one-pot copper-catalyzed domino C-H amination yielding diverse imidazo[4,5-b]pyridines, highlighting an efficient route using simple commercial precursors.
A novel, efficient and one‐pot multicomponent copper‐catalyzed amination of N ‐pyridyl imines is described. This, one‐pot, multicomponent reaction, in which imine acts as a directing group by chelating to the metal core, affords a domino approach for the transformation of the commercial pyridinamines, aldehydes and azide into valuable imidazo[4, 5‐b]pyridines with wide substrate extent and diversity.
No takes yet. Share an insight, caveat, or question.
Nisha et al. (2017) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: