Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 24, 2015Virology JournalOpen Access

Hepatitis C virus genotype and subtype distribution in Chinese chronic hepatitis C patients: nationwide spread of HCV genotypes 3 and 6

View Full Paper
Ask AI
Bookmark
Share

Key result

Among Chinese chronic hepatitis C patients, subtypes 1b (71.96%) and 2a (19.90%) were the most prevalent, while genotypes 3 and 6 have spread nationwide.

Population

1012 chronic hepatitis C patients in China

Design

Cross-sectional

Authors

WJWei JuSYSong YangSFShenghu Feng

Discussion

Loading...

Member takes

Overview

Nationwide HCV genotype shifts may influence therapy responses; extends distribution data but leaves outcome impacts open.

Study Design

Type

Cross-Sectional (n=1,012)

Multicenter

Yes

Structured PICO

P
Population
1,012 treatment-naive chronic hepatitis C patients from 23 centers across China, with a mean age of 48.8 years.
O
Outcome
HCV genotype and subtype distributions

While subtypes 1b and 2a remain the most prevalent HCV subtypes in China, genotypes 3 and 6 have spread nationwide, which may impact antiviral therapy responses.

Limitations

  • Relatively small sample size in central China
  • Patient selection differences compared to previous studies

Cite This Study

Ju et al. (2015) conducted a cross-sectional in Chronic hepatitis C (n=1,012). HCV infection was evaluated on HCV genotype and subtype distribution. Among Chinese chronic hepatitis C patients, subtypes 1b (71.96%) and 2a (19.90%) were the most prevalent, while genotypes 3 and 6 have spread nationwide.

synapsesocial.com/papers/6a903745aec47279de89c91chttps://doi.org/10.1186/s12985-015-0341-1
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Analysis of genetic evolution and molecular transmission of hepatitis C virus in key areas of the southeast coast of China2026
  2. 2Distribution and genotyping of hepatitis C virus (HCV) infection in Gansu province, China2024 · 1 citations
  3. 3Distribution of HCV Genotypes in Patients with Chronic Hepatitis C Infection: A Three-Year Single-Center Retrospective Study2024
  4. 4Genotype Distribution and Migration Patterns of Hepatitis C Virus in Shandong Province, China: Molecular Epidemiology and Phylogenetic Study2025
  5. 5Do differences exist between chronic hepatitis C genotypes 2 and 3?2014 · 5 citations