Protecting the Heart Against Arrhythmias: Potassium Current Physiology and Repolarization Reserve
Key result
Potassium repolarizing current (IK) plays a major role in cardiac repolarization and balances the inward calcium current increased by beta-adrenergic stimulation to prevent QT prolongation.
Population
Squid giant axon and heart cells (historical and physiological review)
Design
Review
Authors
Discussion
Loading...
Member takes
Implication
Potassium currents play a crucial role in cardiac repolarization and provide a repolarization reserve that protects against arrhythmias during adrenergic stimulation.
Structured PICO
P
Population
Squid giant axon and heart cells (historical and physiological review)
Potassium currents play a crucial role in cardiac repolarization and provide a repolarization reserve that protects against arrhythmias during adrenergic stimulation.
Cite This Study
Roden et al. (2005) conducted a review in Arrhythmias. Potassium current (IK) was evaluated. Potassium repolarizing current (IK) plays a major role in cardiac repolarization and balances the inward calcium current increased by beta-adrenergic stimulation to prevent QT prolongation.