Observations on Carotenemia

Article1 February 1958OBSERVATIONS ON CAROTENEMIALORD COHEN, M.D., D.SC., LL.D., F.R.C.P., F.A.C.P. (Hon.)LORD COHEN, M.D., D.SC., LL.D., F.R.C.P., F.A.C.P. (Hon.)Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-48-2-219 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptYellowish pigmentation of the skin (xanthodermia) is most commonly due to jaundice; it is then accompanied by characteristic changes in the mucous membranes, blood, urine and feces. It is, however, seen also when substances such as picric acid, saffron and mepacrine are ingested and stain the tissues. In Great Britain during World War II, when fats were in short supply, xanthodermia was met not infrequently, due to an excessive intake of carrots which followed an exhortation from the Ministry of Food on their virtues. This condition of carotenemia had been earlier described under the namesaurantiasisandcarotenosis cutis, but...Bibliography1. Cadman EF: The interrelationships of the thyroid hormone and carotene and vitamin A (M.D. thesis), 1954, University of Liverpool. Google Scholar2. CamaGoodwin HRTW: Studies in vitamin A. 9. The role of the thyroid in carotene and vitamin A metabolism, Biochem. J. 45: 236, 1949. CrossrefGoogle Scholar3. EscamillaLisserShepardson RFHHC: Internal myxedema; report of a case showing ascites, cardiac, intestinal and bladder atony, menorrhagia, secondary anemia and associated carotenemia, Ann. Int. Med. 9: 297, 1935-36. LinkGoogle Scholar4. Goodwin TW: Comparative biochemistry of carotenoids, 1952, Chapman and Hall, London. Google Scholar5. GreeneBlackford CHLM: Carotenemia, M. Clin. North America 10: 733, 1926. Google Scholar6. LoweMorton JSRA: Vitamins and hormones, Vol. XIV, 1956, Academic Press, Inc., New York, pp. 97-137. Google Scholar7. Moore T: Vitamin A and carotene: distribution of vitamin A and carotene in body of rat, Biochem. J. 25: 275, 1931. CrossrefMedlineGoogle Scholar8. MortonGoodwin RATW: Carotenoids and vitamin A, Brit. M. Bull. 12: 37, 1956. CrossrefMedlineGoogle Scholar9. RosenbergSobel AAE: In vitro conversion of carotene to vitamin A in the isolated small intestine of the rat, Arch. Biochem. and Biophys. 44: 320, 1953. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: LORD COHEN, M.D., D.SC., LL.D., F.R.C.P., F.A.C.P. (Hon.)*Presented at the Thirty-eighth Annual Session of The American College of Physicians, Boston, Massachusetts, April 10, 1957.From the Department of Medicine, The University of Liverpool, Liverpool, England.Requests for reprints should be addressed to The Lord Cohen of Birkenhead, Professor of Medicine, The University of Liverpool, Liverpool, England. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byObservation of Skin Color Change by Carotenosis in Hyperlipidemia PatientEnzymology of vertebrate carotenoid oxygenasesLycopenemia in a patient with thalassemia minorMetabolic Disorders and the SkinA young man with orange handsA Case of Carotenosis Caused by Long Term Excessive Intake of Vegetable JuiceFamilial carotenaemia and carotenodermaHow Nutrients are Affected by GeneticsCarotenaemiaDisorders of Skin ColourLoss-of-Function Mutation in Carotenoid 15,15´-Monooxygenase Identified in a Patient with Hypercarotenemia and Hypovitaminosis A , ,3An orange-tinted baby!A case of carotenemia associated with ingestion of nutrient supplementsCarotenemia Associated with Green Bean IngestionBioavailability of α-+β-carotene in Type 1 diabetic patientsCarotenemia Associated with a Thyroidal Disorder and Menstrual Dysfunction.A Correlation between Carotenemia and Biliary DyskinesiaA case study of carotenemia in anorexia nervosa may support the interrelationship of vitamin A and thyroid hormoneCAROTENODERMA: A POSSIBLE PIT-FALL IN THE IMMUNOPATHOLOGIC DIAGNOSIS OF PEMPHIGUS VULGARISHypercarotenaemia in children with Down's syndromeCutaneous and ocular manifestations of Down syndromeHypercarotenemia Associated with an Oral ContraceptiveCarotenaemia in Alzheimer's disease.Lack of genotoxicity with beta-caroteneEndocrine-skin interactionsHypercarotenemia: A case report and review of the literatureRole of the occupational health service in increasing the uptake of rubella immunisationHypercarotenaemiaHypercarotenaemiaHypercarotenaemiaLung biopsyThe politics of alcoholHypercarotenaemia.CarotenemiaMetabolic carotenaemiaBeta-Carotene Therapy for Erythropoietic Protoporphyria and Other Photosensitivity DiseasesBenign carotenaemia in children.CAROTENOIDS AS FOOD COLORSCAROTENOIDS IN MEDICAL APPLICATIONSCarotenemiaErythropoietic protoporphyria 10 years experienceCarotenemia, skin colour and diabetes mellitusAMELIORATION OF PHOTOSENSITIVITY BY CAROTENEThe hypercarotenemia in anorexia nervosa: a comparison of vitamin A and carotene levels in various forms of menstrual dysfunction and cachexiaA Conspectus of Research on Vitamin A Requirements of ManFamilial Hypercarotinæmia and Hypovitaminosis aHautveränderungen bei inneren ErkrankungenStudies on the Intestinal Absorption of Radioactive β-Carotene and Vitamin A in Man: Conversion of β-carotene into vitamin ACarotenoids: Properties, Occurrence, and Utilization in FoodsKlinische und genetische Untersuchungen an einigen Carotinoiden des menschlichen BlutserumsStudies on the serum total carotenoids, vitamin A and serum colour in Nigerian soldiersAblagerungskrankheiten körpereigener StoffwechselprodukteTHE INFILTRATION OF CAROTENOIDS INTO HUMAN ATHEROMAS AND XANTHOMAS*DAVID H. BLANKENHORN, M.D. 1 February 1958Volume 48, Issue 2 Page: 219-227 Keywords Acid-fast stain Blood Eating Fats Hyperlipidemia Ingestion Mucous membranes Thyroid Urine ePublished: 1 December 2008 Issue Published: 1 February 1958 Copyright & PermissionsCopyright ©, 1958, by The American College of PhysiciansPDF downloadLoading ...