Internal Myxedema; Report of a Case Showing Ascites, Cardiac, Intestinal and Bladder Atony, Menorrhagia, Secondary Anemia and Associated Carotinemia

Article1 September 1935INTERNAL MYXEDEMA; REPORT OF A CASE SHOWING ASCITES, CARDIAC, INTESTINAL AND BLADDER ATONY, MENORRHAGIA, SECONDARY ANEMIA AND ASSOCIATED CAROTINEMIAROBERTO F. ESCAMILLA, M.D., H. LISSER, M.D., F.A.C.P., H. CLARE SHEPARDSON, M.D., F.A.C.P.ROBERTO F. ESCAMILLA, M.D.Search for more papers by this author, H. LISSER, M.D., F.A.C.P.Search for more papers by this author, H. CLARE SHEPARDSON, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-9-3-297 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe classical picture resulting from diminished thyroid activity has long been recognized. But the fact that this endocrinopathy is generalized, involving the internal organs as well as the external covering and configuration of the body, is not so widely appreciated. Thus, alterations in the skin and hair, together with mental sluggishness, are relatively common findings. Occasionally cardiopathies occur for which no morbific factor other than an insufficient thyroid function can be found. More rarely abdominal ascites occurs as part of the syndrome of myxedema. Yet the literature contains a few reports of this finding for which no other etiology was...Bibliography1. EVANS W: Case of myxedema with ascites and atony of urinary bladder, Endocrinology, 1932, xvi, 409-416. CrossrefGoogle Scholar2. ALTHAUSENBISKINDKERR TLGRWJ: Rose Bengal test of hepatic function; spectroscopic method, Jr. Lab. and Clin. Med., 1933, xviii, 954-958. Google Scholar3. MUSSIO FOURNIER MJ: Syndrome hydropigène et insuffisance thyoïdienne, Bull. Acad. de méd., Paris, 1925, xciii, 691-694. Google Scholar4. MARSH HE: Myxedematous ascites removed by thyroid extract, Am. Jr. Med. Sci., 1926, clxxii, 585-588. CrossrefGoogle Scholar5. DAVIDSON JR: Adolescent myxedema accompanied by nephrosis, and in one case, tetany, Canad. Med. Assoc. Jr., 1925, xv, 598-600. Adolescent myxedema, accompanied by nephrosis and by tetany of parathyroid origin, treated with thyroid and Collip's parathyroid extract, ibid., 1925, xv, 803-808. Nephrosis of thyroid origin, ibid., 1926, xvi, 1059-1063; ibid., 1928, xviii, 161-164. Google Scholar6. BERETERVIDEHERRERA JJLM: Ascitïs e insuficiencia tiroidea, Arch. argent. de enferm. d. ap. digest. y de la nutrición, 1932, vii, 353-358. Google Scholar7. EPSTEIN AA: Studies on the chemistry of serous effusions, Jr. Exper. Med., 1914, xx, 334-345. CrossrefGoogle Scholar8. SALVESENLINDER HAGC: Inorganic bases and phosphates in relation to the protein of blood and other body fluids in Bright's disease and in heart failure, Jr. Biol. Chem., 1923, lviii, 617-634. CrossrefGoogle Scholar9. FOORDYOUNGBERGWETMORE AGGEV: Chemistry and cytology of serous fluids, Jr. Lab. and Clin. Med., 1929, xiv, 417-428. Google Scholar10. MACHEBOEUFFETHKE MAN: Recherches sur les lipides et les protéides des liquides d'épanchements non-purulents des séreuses, Bull. Soc. chim. biol., 1932, xiv, 507-520. Google Scholar11. BECK HG: Association of urologic lesions with hypothyroidism, Endocrinology, 1927, xi, 438-444. CrossrefGoogle Scholar12. ZONDEK H: Das Myxödemherz, München. med. Wchnschr., 1918, lxv, 1180-1182. Google Scholar13. LISSERANDERSON HEM: Three cases of adult myxedema in women reported for the purpose of calling attention to their widely different symptomatology and clinical findings, Endocrinology, 1931, xv, 365-381. CrossrefGoogle Scholar14. AYMANROSENBLUMFALCON-LESSES DHM: "Myxedema heart" without evidence of cardiac insufficiency, Jr. Am. Med. Assoc., 1932, xcviii, 1721-1725. CrossrefGoogle Scholar15. GALLAGHER JR: Myxedema heart disease—with report of one case, Yale Jr. Biol. and Med., 1932, v, 75-80. Google Scholar16. LERMANCLARKMEANS JRJJH: Heart in myxedema, ANN. INT. MED., 1933, vi, 1251-1271. LinkGoogle Scholar17. FAHR G: Myxedema heart, Jr. Am. Med. Assoc., 1925, lxxxiv, 345-349. CrossrefGoogle Scholar18. CHRISTIAN HA: Heart and its management in myxedema, Rhode Island Med. Jr., 1925, viii, 109-118. Google Scholar19. STURGISWHITING CCWB: Treatment and prognosis in myxedema, Jr. Am. Med. Assoc., 1925, lxxxv, 2013-2017. CrossrefGoogle Scholar20. FISHBERG AM: Arteriosclerosis in thyroid deficiency, Jr. Am. Med. Assoc., 1924, lxxxii, 463-464. CrossrefGoogle Scholar21. DUDEN CW: Myxedema with cardiac decompensation and hypertension which disappeared under thyroid medication, Jr. Missouri Med. Assoc., 1929, xxvi, 25-27. Google Scholar22. THOMPSONDICKIEMORRISHILKEVITCH WOLFAEBH: High incidence of hypertension in toxic goiter and in myxedema, Endocrinology, 1931, xv, 265-272. CrossrefGoogle Scholar23. THACHERWHITE CPD: Electrocardiogram in myxedema, Am. Jr. Med. Sci., 1926, clxxi, 61-66. CrossrefGoogle Scholar24. LISSER H: Clinical indications for proper use of thyroid substance, Internat. Clin., 1933, iv, 66-101. Google Scholar25. FAHR G: Myxedema heart, Am. Heart Jr., 1927, iii, 14-30. CrossrefGoogle Scholar26. NOBELROSENBLÜTHSAMET EAB: Das Elektrokardiogramm des kindlichen Myxödems, Ztschr. f. d. ges. exper. Med., 1924, xliii, 332-341. CrossrefGoogle Scholar27. MATHERS AT: A case of myxedema, Canad. Med. Assoc. Jr., 1920, x, 859. Google Scholar28. DEUSCH G: Thyroid and motility of intestines, Deutsch. Arch. f. klin. Med., 1923, cxlii, 1-31; Abstr., Jr. Am. Med. Assoc., 1923, lxxxi, 171. Google Scholar29. BROWN TR: Hypothyroidism as a cause of intractable constipation, Trans. Assoc. Am. Phys., 1926, xli, 162. Google Scholar30. BROWN TR: Effect of hypothyroidism on gastric and intestinal function, Jr. Am. Med. Assoc., 1931, xcvii, 511-513. CrossrefGoogle Scholar31. WOHL MG: Hypothyroidism, with special reference to gastrointestinal tract, Med. Clin. N. Am., 1931, xiv, 1017-1023. Google Scholar32. HINTON JW: Abdominal pain due to hypothyroidism, Jr. Am. Med. Assoc., 1932, xcviii, 1702-1703. CrossrefGoogle Scholar33. EMERY ES: Blood in myxedema, Am. Jr. Med. Sci., 1923, clxv, 577-583. CrossrefGoogle Scholar34. MACKENZIE GM: Anemia in hypothyroidism, Jr. Am. Med. Assoc., 1926, lxxxvi, 462-464. CrossrefGoogle Scholar35. STONE CT: Occurrence of anemia in myxedema, ANN. INT. MED., 1928, ii, 215-221. Google Scholar36. LERMANMEANS JJH: Treatment of anemia of myxedema, Endocrinology, 1932, xvi, 533-540. CrossrefGoogle Scholar37. MEANSLERMANCASTLE JHJWB: Coexistence of myxedema and pernicious anemia, New England Jr. Med., 1931, cciv, 243-248. CrossrefGoogle Scholar38. SALZMAN S: Hypothyroidism a factor in certain types of uterine hemorrhage, Am. Jr. Obst., 1916, lxxiv, 812-818. Google Scholar39. LISSER H: In BLUMER, G.: Bedside diagnosis, 1928, W. B. Saunders, Philadelphia. Google Scholar40. GARDINER-HILLSMITH HJF: Menorrhagia as symptom of myxedema, Lancet, 1927, i, 862-864. CrossrefGoogle Scholar41. WATERSWILLIAMS WCGA: Menorrhagia due to hypothyroidism, Am. Jr. Obst. and Gynec., 1932, xxiii, 489-493. CrossrefGoogle Scholar42. RABINOWITCH IM: Carotinemia and diabetes, Canad. Med. Assoc. Jr., 1928, xviii, 527-530. Google Scholar43. ROWE AW: Endocrine studies: association of hepatic dysfunction with thyroid failure, Endocrinology, 1933, xvii, 1-22. CrossrefGoogle Scholar44. GARDINER-HILLBRETTSMITH HPCJF: Carbohydrate tolerance in myxedema, Quart. Jr. Med., 1925, xviii, 327-334. CrossrefGoogle Scholar45. KING JT: Hypothyroidism, Southern Med. Jr., 1924, xvii, 662-669. CrossrefGoogle Scholar46. LAWRENCE CH: Studies in endocrinology. I. Hypothyroidism with and without myxedema, Boston Med. and Surg. Jr., 1924, cxc, 307-312. CrossrefGoogle Scholar47. LAWRENCE CH: Thyroid failure without myxedema, Med. Clin. N. Am., 1925, viii, 1779-1788. Google Scholar48. HIGGINS WH: Incipient hypothyroidism; clinical study, Jr. Am. Med. Assoc., 1925, lxxxv, 1015-1017. CrossrefGoogle Scholar49. BLUMGARTEN AS: Unusual forms of hypothyroidism, Med. Clin. N. Am., 1928, xii, 593-602. Google Scholar50. MCKEAN RM: Hypothyroidism without myxedema; its recognition and treatment, Jr. Michigan Med. Soc., 1929, xxviii, 128-131. Google Scholar51. WARFIELD LM: Hypothyroidism, Jr. Am. Med. Assoc., 1930, xcv, 1076-1080. CrossrefGoogle Scholar52. HENSEL CN: Non-myxedematous hypothyroidism, Minnesota Med., 1931, xiv, 221-223. Google Scholar53. THURMONTHOMPSON FMWO: Low basal metabolism without myxedema, Arch. Int. Med., 1930, xlvi, 879-897. CrossrefGoogle Scholar54. YOUMANSRIVEN JBSS: Hypothyroidism without myxedema, ANN. INT. MED., 1932, v, 1497-1505. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: San Francisco, California*Read at the Philadelphia meeting of the American College of Physicians, April 29, 1935.From the Department of Medicine of the University of California Medical School, San Francisco, Calif. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySymptomatic Ascites in a Patient with Hypothyroidism of Short DurationAcute colonic surgery and unrecognized hypothyroidism: A warningAn Unusual Case of Myxedema Megacolon With Features of Ischemic and Pseudomembranous ColitisValue of clinical features for distinguishing myxedema ascites from other forms of ascitesEFFUSIONS INTO BODY CAVITIES IN HYPOTHYROIDISMSyndromeASCITES IN HYPOTHYROIDISMAblagerungskrankheiten körpereigener StoffwechselprodukteHypothyreosen — Strumen — ThyreoiditidenOBSERVATIONS ON CAROTENEMIA*LORD COHEN, M.D., D.SC., LL.D., F.R.C.P., F.A.C.P. 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