Answers are grounded in this paper and cite their sources.
Bacteria under pressure! An efficient synthesis of the enantiopure tricyclic core of a recently discovered antibiotic, platencin, has been developed. This synthesis highlights a novel high-pressure Diels–Alder reaction of the flavoring agent (S)-(−)-perillaldehyde and an efficient SmI2-mediated pinacol cyclization for the construction of the bicyclo[2.2.2]octane framework (see scheme).
No takes yet. Share an insight, caveat, or question.
Waalboer et al. (2008) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: