Key result
An increased waist-hip ratio was associated with a 2.75-fold higher odds of having significant coronary artery disease in patients presenting with acute STEMI.
Why the study?
Does increased waist-hip ratio associate with greater angiographic severity of coronary artery disease in patients with acute STEMI?
Cross-Sectional (n=105)
No
Does increased waist-hip ratio associate with greater angiographic severity of coronary artery disease in patients with acute STEMI?
Odds Ratio: 2.75 (95% CI 1.2–4.979)
Absolute Event Rate: 77.8% vs 29.4%
p-value: p=0.03
Increased waist-hip ratio is strongly associated with greater angiographic severity of coronary artery disease in patients presenting with acute STEMI.
WHR may identify CAD risk in Bangladeshis; leaves open its added value to standard models in prospective studies.
Objective: Coronary artery disease (CAD) is rising in South Asia and is taking a more malignant proportion in South Asians than in Caucasians. Having a similar socioeconomic and cultural background, the scenario is same in Bangladesh. Obesity, especially abdominal is concerned as an important and modifiable risk factor for CAD which is now also raising both in developed and under developed countries. Waist-Hip ratio (WHR) is considered as an important tool for assessing abdominal obesity. The aim of this study is to evaluate the association between WHR and the severity of CAD of acute ST-segment elevation myocardial infarction (STEMI) patients so that primary prevention, early detection and proper management strategy can be taken to reduce the disease burden, morbidity and mortality.Methods: This cross sectional observational study was carried out among 105 patients with acute STEMI who received thrombolytic and underwent coronary angiography (CAG) at National Institute of Cardiovascular Diseases (NICVD), Dhaka from May, 2016 to November, 2016. They were divided into two groups, Group I (normal WHR) = 51 and group II (increased WHR) = 54, according to WHR level. Angiographic severity of coronary artery disease was assessed by vessel score and Genseni’s score.Results: Significant positive correlation was found between WHR and vessel score (r= 0.62, p=0.003). Moderate to severe CAD patients were significantly higher in increased WHR group than in normal WHR group (77.8% vs. 29.4%, p=<0.001). Significant positive correlation was also found between WHR and Genseni’s score (r= 0.71, p=0.001). Logistic regression analysis showed that a patient with increased WHR had 2.75 times higher risk of having significant CAD compared with those with the normal WHR.Conclusions: Increased WHR group had more significant coronary artery disease in terms of vessel score and Genseni’s score and can be considered as a predictor of the severity of the CAD disease in acute STEMI patients.Bangladesh Heart Journal 2017; 32(2) : 70-76
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Hossain et al. (2018) conducted a cross-sectional in Acute ST-Segment Elevation Myocardial Infarction (STEMI) (n=105). Increased Waist-Hip Ratio vs. Normal Waist-Hip Ratio was evaluated on Significant coronary artery disease (Gensini's score ≥ 36) (OR 2.75, 95% CI 1.200-4.979, p=0.03). An increased waist-hip ratio was associated with a 2.75-fold higher odds of having significant coronary artery disease in patients presenting with acute STEMI.
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