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April 8, 2025BMC NephrologyOpen Access

The transition of patients with advanced CKD from predialysis to dialysis is a dynamic process shaped by personal, dialysis-related, interpersonal, community, and societal factors, requiring tailored multidisciplinary support strategies.

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Why the study?

A smooth transition to dialysis is essential for survival and quality of life in patients with advanced CKD, warranting a framework to illuminate transition experiences and provide intervention strategies.

Design

Theory-guided integrative review

Key result

The transition of patients with advanced CKD from predialysis to dialysis is a dynamic process shaped by personal, dialysis-related, interpersonal, community, and societal factors, requiring tailored multidisciplinary support strategies.

Authors

XWXuefei WangKTKe TianJHJin Hu

Discussion

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Overview

The CKD transition framework may inform tailored predialysis support; leaves open prospective validation before practice change.

Study Design

Type

Systematic Review (n=21)

Structured PICO

P
Population
An integrative review of 21 studies evaluating the transition experiences and care strategies for patients with advanced chronic kidney disease progressing from predialysis to dialysis.
I
Intervention
Transitional care interventions including predialysis education, multidisciplinary care, home visits, and virtual care.
O
Outcome
Transition experiences, facilitators, inhibitors, and response patterns (including process indicators like health literacy and outcome indicators like emergency dialysis rates and hospitalization).

This integrative review provides a comprehensive framework for understanding the transition from predialysis to dialysis in advanced CKD, highlighting the need for tailored, multidisciplinary strategies to reduce emergency dialysis and improve patient outcomes.

Limitations

  • Majority of included studies lacked explicit grounding in established theoretical frameworks.
  • Scarcity of RCTs restricts causal inferences about intervention efficacy.
  • Few studies holistically examined patient outcomes across the transition continuum.
  • Most included studies were conducted in high-income countries, limiting applicability to underserved populations.

Cite This Study

Wang et al. (2025) conducted a systematic review in Advanced chronic kidney disease (n=21). Transitional care and predialysis education vs. Standard care or no structured transition care was evaluated. The transition of patients with advanced CKD from predialysis to dialysis is a dynamic process shaped by personal, dialysis-related, interpersonal, community, and societal factors, requiring tailored multidisciplinary support strategies.

synapsesocial.com/papers/6a90495885f80aee81dd7bdehttps://doi.org/10.1186/s12882-025-04104-4
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Pediatric to adult transition in chronic kidney disease: a scoping review2026
  2. 2Optimization of Dialysis Modality Transitions for Improved Patient Care2019 · 37 citations
  3. 3Renal staffs’ understanding of patients’ experiences of transition from peritoneal dialysis to in-centre haemodialysis and their views on service improvement: A multi-site qualitative study in England and Australia2021 · 7 citations
  4. 4TRANSITION FROM MATERNAL CHRONIC RENAL FAILURE TO PERITONEAL DIALYSIS TREATMENT2024
  5. 5Improving Transition of Care for Pediatric Patients With Chronic Kidney Disease: A Pilot Project2024