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December 1, 1977Acta Physiologica Scandinavica

Transmembrane Potential Measurements as an Indicator of Heterogeneous Distribution of Nutritive Blood Flow in Skeletal Muscle during Shock

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Population

Dogs subjected to shock induced by exteriorization of the small intestine for 3 hours

Comparison

Shock induction and complete tourniquet ischemia vs Control animals

Design

Preclinical

Follow-up

3-4 hours

Authors

HHH. HaljamäeLund UniversityEJEva JennischeUniversity of GothenburgAMAlf Medgeård

Discussion

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Implication

No direct clinical implications from this animal model; leaves open whether heterogeneous membrane changes affect human shock outcomes.

Structured PICO

P
Population
Dogs subjected to shock induced by exteriorization of the small intestine for 3 hours
I
Intervention
Shock induction (exteriorization of small intestine) and complete tourniquet ischemia
C
Comparator
Control animals
O
Outcome
Cellular transmembrane potential variations of single skeletal muscle cellssurrogate

Repeated transmembrane potential registrations can reveal the variable state of adjacent cells subjected to heterogeneous nutritive blood flow during shock.

Cite This Study

Haljamäe et al. (1977) studied this question.

synapsesocial.com/papers/6a90505b3dd9003d79c912e2https://doi.org/10.1111/j.1748-1716.1977.tb06029.x
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Also Consider

Synapse has enriched one closely related paper. Consider it for comparative context:

  1. 1Alterations in Cellular Membrane Function During Hemorrhagic Shock in Primates1972 · 171 citations