Key result
The EVA-Tyrol study is a planned non-randomized controlled trial that will evaluate the efficacy of a multi-layer cardiovascular health promotion program in 2,000 adolescents.
Why the study?
Atherosclerosis begins early in life, suggesting that cardiovascular disease prevention programs may need to start in childhood to raise risk awareness and promote healthy lifestyles.
Does a multi-layer health promotion program improve cardiovascular health metrics in adolescents?
Does a multi-layer health promotion program improve cardiovascular health metrics in adolescents?
The EVA-Tyrol study protocol outlines a non-randomized controlled trial to evaluate the efficacy of a multi-layer cardiovascular health promotion program in improving AHA health metrics among adolescents.
May support starting CVD prevention in adolescence; leaves open efficacy of multi-layer school programs in randomized trials.
BACKGROUND: According to the World Health Organization, cardiovascular diseases (CVDs) are the leading non-communicable cause of death. Awareness of the individual risk profile is crucial to implement a healthy lifestyle and prevent CVDs. Multiple studies demonstrated that atherosclerosis, the main cause of CVDs, begins early in life. Therefore, it may be necessary to start prevention programs already in childhood. METHODS: The EVA-Tyrol study is a population-based non-randomized controlled trial that will prospectively enroll 2000 participants from high schools and training companies in North- and East-Tyrol (Austria) and South-Tyrol (Italy). Participants will be assigned to either an intervention (n = 1500) or a control (n = 500) group. Intervention group participants will be enrolled at the 10th school grade (mean age 15-16 years), undergo two examinations within a two-year interval, with follow-up at the 12th grade (mean ages 17-18 years). Control group participants will be enrolled at the 12th grade (mean age 17-18 years). Medical examination will include anthropometric measurements, comprehensive lifestyle and dietary questionnaires, a fasting blood sample, high-resolution ultrasound of the carotid arteries, and measurement of carotid-femoral pulse wave velocity. Active intervention will consist of (1) enhancing knowledge about CVDs, (2) individual medical counseling based on the results of the baseline examination, (3) an online health promotion tool and (4) involvement of participants in planning and implementation of health promotion projects. Effectiveness of the intervention will be assessed by comparing the proportion subjects with ideal health metrics as defined by the American Heart Association between study groups. DISCUSSION: This study aims to improve cardiovascular health in Tyrolean adolescents by demonstrating the efficacy of a multi-layer health promotion program and may yield novel insights into the prevalence of vascular risk conditions and mechanisms of early vascular pathologies in adolescents. TRIAL REGISTRATION: EVA-Tyrol has been retrospectively registered at clinicaltrials.gov under NCT03929692 since April 29, 2019.
No takes yet. Share an insight, caveat, or question.
Bernar et al. (2020) studied Cardiovascular risk (n=2,000). Cardiovascular health promotion program vs. No health promotion program was evaluated on Difference in the proportion of subjects with ideal AHA health metrics between study groups. The EVA-Tyrol study is a planned non-randomized controlled trial that will evaluate the efficacy of a multi-layer cardiovascular health promotion program in 2,000 adolescents.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: