Population
Yeast (Saccharomyces cerevisiae)
Comparison
Deletion or overexpression of MYO4 or MYO2 vs Wild-type yeast or other myosin/actin/secretory…
Design
Preclinical
Authors
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No immediate clinical implications; leaves open relevance of yeast myosin dosage effects to mammalian systems.
Identification of MYO4 as a second class V myosin gene in yeast, where its overexpression, but not deletion, causes morphological abnormalities.
Haarer et al. (1994) studied this question.
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