Answers are grounded in this paper and cite their sources.
Design and applications of multimetallic bifunctional asymmetric catalysts based on the proximity-effect-control concept are described. Suitable design of chiral ligands and selection of metals were important to realize cooperative bimetallic catalysis. Homo-multimetallic complexes, using linked-BINOLs (Zn, In, Y, and La), as well as hetero-multimetallic complexes, using a dinucleating Schiff base, BINOL, and pybox (Cu–Sm, La–Li, and Y–Li), were developed for asymmetric direct aldol reactions, Michael reactions, direct Mannich-type reactions, nitro-Mannich-type reaction, aza-Michael reactions, kinetic resolution of tert-nitroaldols, and cyanation reactions. Synergistic effects of two or more metals played a key role in promoting the reactions in high reactivity and enantioselectivity.
No takes yet. Share an insight, caveat, or question.
Matsunaga et al. (2008) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: