Administration of ammonium carbamate either orally or intravenously produced symptoms in ruminating lambs similar to those observed during acute urea toxicity. It is proposed that urea toxicity in the ruminant is not due to ammonia, but to ammonium carbamate. It is suggested that conditions exist in the rumen after the oral administration of urea which would lead to the formation of ammonium carbamate.
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Hale et al. (1955) studied this question.