Population
20 adults and 55 children for serological testing, 20 adults for T-cell response testing, and rabbit models…
Comparison
Recombinant human parechovirus type 1 capsid… vs GST control protein or preimmune sera.
Design
Preclinical
Authors
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May support VP3-based EIA development in research; leaves open human diagnostic validation.
Recombinant HPEV1 VP3 capsid protein is a highly sensitive and specific antigen for detecting HPEV1 antibodies in enzyme immunoassays, offering a potential alternative to laborious neutralization tests.
Marttila et al. (2003) studied this question.
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