Why the study?
What is the cardiac function and myocardial injury profile in African children with severe Plasmodium falciparum malaria?
What is the cardiac function and myocardial injury profile in African children with severe Plasmodium falciparum malaria?
In children with severe malaria, elevated cardiac index is a physiologic response to anemia that normalizes with treatment, and despite evidence of myocardial injury, systolic function is largely preserved.
Myocardial dysfunction uncommon in severe pediatric malaria; leaves open optimal fluid strategies pending randomized trials.
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Kotlyar et al. (2017) studied this question.
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