Key result
Warfarin triggers extensive deep tissue necrosis involving tendons and bone beyond superficial skin involvement.
Why the study?
Warfarin-induced tissue necrosis (WITN) is a rare but serious complication of warfarin therapy with limited literature and unclear pathophysiology.
Case Report (n=1)
No
Warfarin-induced skin necrosis can extend well beyond the skin to involve deeper tissues including tendons and bones, indicating the terminology 'Warfarin-Induced Tissue Necrosis' is more clinically accurate.
Answers are grounded in this paper and cite their sources.
May warrant deeper tissue assessment in warfarin necrosis; leaves open whether revised nomenclature improves recognition or outcomes.
Volume 1 | Issue 1 Warfarin-Induced Tissue Necrosis (WITN): Case Report and Literature Review, A Proposed Name Change Simman R*1, Gould N2 and Jackson SE3 1Plastic and Reconstructive Surgery, Pharmacology and Toxicology, Wright State University Boonshoft School of Medicine, Dayton Ohio 2Family Medicine Program, Grand View Hospital, Kettering Health Network. Dayton, Ohio 3Clinical Assistant Professor of Internal Medicine, Wright State University Boonshoft School of Medicine, Dayton, Ohio *Corresponding author: Simman R, Department of Surgery, Wright State University Boonshoft School of Medicine, E-mail: plasticsimman@yahoo.
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Simman et al. (2016) conducted a case report in Warfarin-Induced Tissue Necrosis (n=1). Warfarin was evaluated on Development of tissue necrosis. Warfarin therapy induced extensive deep tissue necrosis involving subcutaneous tissue, tendons, and bones, prompting a proposed name change to Warfarin-Induced Tissue Necrosis.
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