Observational patch-test study identifies contact allergy to brown stocking dye in eczema patients, highlighting cross-reactivity with azo dyes and p-phenylenediamine.
Fourteen eczema patients, 13 women and one man, were found to have contact allergy to a brown stocking dye which is a mixture of nitro- and aminodiazobenzene and aminoanthraquinone dyes. Eleven of the patients reacted to p-phenylenediamine; nine of 12 tested reacted to aminoazobenzene, nine to Disperse Orange 3 and four to Disperse Yellow 3. Positive epicutaneous test reactions to the dye were found in five of 362 consecutive eczema patients tested (1.4%).
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Kousa et al. (1980) studied this question.
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