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Reports patch-test results revealing common allergens in a large population, indicating trends in allergic reactions.
Background:Patch testing is the most worthwhile diagnostic tool for the evaluation of patients with suspected allergic contact dermatitis. Objective:This study reports patch-testing results from July 1, 1998, to December 31, 2000, by the North American Contact Dermatitis Group. Methods:Patients were tested with the same screening series of allergens, using a standardized patch-testing technique. The data from these patients were recorded on a standard computer entry form and analyzed. Results:Fifty allergens were tested on over 5,800 patients. Amidoamine, benzophenone-3, and iodopropynyl butylcarbamate were the new allergens. The top 10 allergens in frequency of positive reactions were identical to those of our 1996-to 1998-study period. The incidence of allergic nickel reactions continues to go up, leading all the test substances by 16.2%. Conclusion:Our findings reinforce the need for a more comprehensive group of diagnostic allergens than is found in the T.R.U.E. TEST, which is sold in the United States.
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Marks et al. (2003) studied this question.
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