Population
Rabbit skeletal myofibrils
Comparison
Treatment with excess troponin T, chicken breast… vs Intact myofibrils
Design
Preclinical
Authors
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Does not support clinical use; leaves open cardiac troponin exchange effects pending in vivo studies.
The study demonstrates that troponin T or its 26K fragment can selectively replace the entire troponin complex in skeletal myofibrils, altering calcium sensitivity.
Shiraishi et al. (1992) studied this question.