February 22, 2012Virology JournalOpen Access

Genetic relationships and epidemiological links between wild type 1 poliovirus isolates in Pakistan and Afghanistan

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Population

111 wild type 1 poliovirus isolates from faecal samples of Acute Flaccid Paralysis patients and contacts in…

Authors

MAMehar AngezQuaid-i-Azam University SSShahzad ShaukatWorld Health Organization - Pakistan MAMuhammad Masroor AlamWorld Health Organization - Pakistan

Discussion

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Implication

Supports synchronized cross-border polio vaccination; leaves open whether transmission persists amid updated eradication efforts.

Structured PICO

Population

111 wild type 1 poliovirus isolates from faecal samples of Acute Flaccid Paralysis (AFP) patients and contacts in Pakistan and Afghanistan during 2005-2007 (out of 25,965 AFP cases from Pakistan and 4,485 from Afghanistan).

Outcome

Genetic relatedness and transmission links among wild type 1 polioviruses based on entire VP1 region sequencing.

Genetic sequencing of wild type 1 poliovirus isolates from 2005-2007 demonstrates persistent, cross-border transmission between Pakistan and Afghanistan, highlighting the need for synchronized mass immunization.

Cite This Study

Angez et al. (2012) studied this question.

synapsesocial.com/papers/6a906ddbd68f3313dd841e9a https://doi.org/10.1186/1743-422x-9-51

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Genetic relationships and epidemiological links between wild type 1 poliovirus isolates in Pakistan and Afghanistan

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Genetic relationships and epidemiological links between wild type 1 poliovirus isolates in Pakistan and Afghanistan

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider