Letters and Corrections1 April 1983The Toxic Shock Syndrome and Streptococcal Pyrogenic ExotoxinsRICHARD WILLOUGHBY, M.D., RICHARD N. GREENBERG, M.D.RICHARD WILLOUGHBY, M.D., RICHARD N. GREENBERG, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-98-4-559_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Our reading of Part 2 of the June 1982 issue on toxic shock syndrome suggested to us that other organisms may produce pyrogenic exotoxins and occasionally cause toxic shock syndrome. As stated in the accompanying editorial, culture results are available in less than one third of all cases currently reported to the Centers for Disease Control. Although Staphylococcus aureus alone was reported in over 90% of the cases for which there are culture results (1) it may be that other organisms are overlooked and are not reported.Streptococcal pyrogenic exotoxins have been well described, yet these substances...References1. WANNAMAKER L. Toxic shock: problems in definition and diagnosis of a new syndrome [Editorial]. Ann Intern Med. 1982;96(6 pt 1):775-7. LinkGoogle Scholar2. DICK G and DICK G. A skin test for susceptibility to scarlet fever. JAMA. 1924;82:265-6. CrossrefGoogle Scholar3. WATSON D. Characterization and pathobiological properties of group A streptococcal pyrogenic exotoxins. In: PARKER MT, ed. Pathogenic Streptococci. England: Reedbooks; 1979:62-3. Google Scholar4. SCHLIEVERT P and KELLY J. Staphylococcal pyrogenic exotoxin type C: further characterization. Ann Intern Med. 1982;96:(6 pt 2):982-6. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: RICHARD WILLOUGHBY, M.D.; RICHARD N. 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