December 20, 2017The Journal of Infectious DiseasesOpen Access

Isolation of Vaccine-Like Poliovirus Strains in Sewage Samples From the United Kingdom

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Population

Sewage samples collected in London, United Kingdom, from June 2016 to May 2017

Design

Other

Authors

MMManasi MajumdarEnvironment Agency DKDimitra KlapsaEnvironment Agency TWThomas WiltonImperial College Healthcare NHS Trust

Discussion

Member takes

Implication

NGS sewage surveillance may enhance HEV detection; leaves open its role in routine global monitoring.

Structured PICO

Population

Sewage samples collected in London, United Kingdom, from June 2016 to May 2017

Intervention

Environmental surveillance using next-generation sequencing (NGS) and two processing methods (2-phase aqueous separation system and size exclusion by filtration and centrifugation)

Outcome

Detection and whole-genome sequencing of human enteroviruses (HEVs), specifically poliovirus (PV) strains

Next-generation sequencing of sewage samples provides a highly sensitive method for environmental surveillance of poliovirus and other human enteroviruses to support global eradication efforts.

Cite This Study

Majumdar et al. (2017) studied this question.

synapsesocial.com/papers/6a9072a5b0770bec3fc7a330 https://doi.org/10.1093/infdis/jix667

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Isolation of Vaccine-Like Poliovirus Strains in Sewage Samples From the United Kingdom

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Isolation of Vaccine-Like Poliovirus Strains in Sewage Samples From the United Kingdom

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider