Correlation between Intravascular Ultrasound and Multi-Detector Computed Tomography in Assessment of Coronary Lesion in Patients with Ischemic Heart Disease

Hany Hassan Ebaid

doi:10.19080/jocct.2019.13.555871

April 18, 2019Journal of Cardiology & Cardiovascular TherapyOpen Access

Correlation between Intravascular Ultrasound and Multi-Detector Computed Tomography in Assessment of Coronary Lesion in Patients with Ischemic Heart Disease

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Why the study?

Does Multi-Detector Computed Tomography (MDCT) accurately correlate with Intravascular Ultrasound (IVUS) for the assessment of coronary lesion dimensions in patients with ischemic heart disease?

Structured PICO

Does Multi-Detector Computed Tomography (MDCT) accurately correlate with Intravascular Ultrasound (IVUS) for the assessment of coronary lesion dimensions in patients with ischemic heart disease?

P

Population

50 patients with ischemic heart disease (chronic stable angina or unstable angina) planned for coronary angiography, mean age 56.3 years, 72% male. Key exclusions: acute myocardial infarction, previous stenting, documented allergy to intravenous contrast medium, renal insufficiency (creatinine >1.5 mg/dl), suspected pregnancy, heart rate >80 bpm or arrhythmias, high risk of bleeding, heavy calcification (Ca score >600), and improper breath holders.

I

Intervention

Multi-Detector Computed Tomography (MDCT) performed within 72 hours before coronary angiography

C

Comparator

Intravascular Ultrasound (IVUS) performed during coronary angiography

O

Outcome

Correlation of quantitative coronary lumen parameters (minimal luminal area, minimal luminal diameter, and plaque burden) between MDCT and IVUS at patient, vessel, and segment levelssurrogate

MDCT is a reliable non-invasive imaging modality that significantly correlates with invasive IVUS for assessing coronary lumen dimensions and plaque burden in patients with ischemic heart disease.

Limitations

Increasing motions artifacts in patients with heart rate more than 70 bpm during MDCT limited the study even with the use of beta blockers
High prevalence of risk factors in the study population limited generalizability to multiple clinical scenarios
Excluding patients with coronary calcium score >600 could alter the correlation between MDCT and IVUS measurements

Implication

May support hypothesis generation in cardiology; leaves open need for confirmatory randomized studies.

Abstract

scholarly articles on cardiology Journal of Cardiology & Cardiovascular Therapy is an Open Access, international peer reviewed journal launched from Juniper Publishers. Cardiology is a branch of medicine deals with the disorders of heart that keeps cardiologists up to date with advances in the diagnosis and treatment of cardiovascular diseases.

Discussion

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Cite This Study

Hany Hassan Ebaid (2019) studied this question.

synapsesocial.com/papers/6a907321e6af338650dd8d2b https://doi.org/10.19080/jocct.2019.13.555871

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Correlation between Intravascular Ultrasound and Multi-Detector Computed Tomography in Assessment of Coronary Lesion in Patients with Ischemic Heart Disease

Structured PICO

Limitations

Implication

Abstract

Discussion

Cite This Study

Correlation between Intravascular Ultrasound and Multi-Detector Computed Tomography in Assessment of Coronary Lesion in Patients with Ischemic Heart Disease

Structured PICO

Limitations

Implication

Abstract

Discussion

Cite This Study

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