Population
Primary cultures of bovine retinal pigmented epithelial (RPE) cells
Comparison
Nitric oxide released by SIN-1 or endogenous NO… vs Control conditions without NO, or with NO…
Design
Preclinical
Authors
Loading...
May link nitric oxide to inflammation-driven photoreceptor loss; leaves open in vivo confirmation and clinical relevance.
Nitric oxide decreases rod outer segment phagocytosis by retinal pigmented epithelial cells, suggesting a mechanism by which retinal inflammation could lead to photoreceptor degeneration.
Becquet et al. (1994) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: