A strain of Plasmodium berghei, Kasapa S.P. 7307, recently isolated from the Belgian Congo, has been cyclically transmitted through Anopheles quadrimaculatus, Anopheles aztecus, and young white rats three successive times. Sporozoites from crushed oocysts of heavily infected mosquitoes were used as inoculum. The newly isolated “passage” strains were designated as N.Y.U.1, N.Y.U.2, and N.Y.U.3 Strains of P. berghei (New York University Strains). The pre-patent period in four sporozoite infected young rats were: 71 hours, 96 hours, 8 days, and 10 days. Parasites found in the peripheral blood at the early “flooding” period of 71 hours after sporozoite inoculation are described in detail. A description is given of the different developmental stages of the sporozonic cycle as observed in the newly isolated strains, under experimental conditions.
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Yoeli et al. (1960) studied this question.