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April 20, 2020CirculationOpen Access

Exercise and Coronary Atherosclerosis

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Why the study?

Physical activity reduces cardiovascular event risks, but studies report an increased prevalence of coronary atherosclerosis and calcification among middle-aged and older athletes. This review aims to understand the potential adverse effects of high-dose exercise training on coronary arteries and guide clinical management.

Does physical activity and exercise training increase coronary atherosclerosis in middle-aged and older athletes?

Population

Middle-aged and older athletes

Comparison

Athletes vs controls, and most active vs less active athletes

Design

Literature review

Authors

VAVincent L. AengevaerenAMArend MosterdSSSanjay Sharma

Discussion

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Member takes

Overview

Higher CAC in athletes warrants no change in exercise advice; leaves open whether plaques increase events versus sedentary peers.

Structured PICO

Does physical activity and exercise training increase coronary atherosclerosis in middle-aged and older athletes?

P
Population
Middle-aged and older athletes
I
Intervention
Physical activity and exercise training (highest doses)
C
Comparator
Controls and less active athletes
O
Outcome
Coronary atherosclerosis (measured as coronary artery calcification and atherosclerotic plaques)surrogate

While high-dose exercise in middle-aged and older athletes is associated with increased coronary artery calcification, the plaques tend to be more calcified and less mixed, suggesting a more benign composition.

Cite This Study

Aengevaeren et al. (2020) studied this question.

synapsesocial.com/papers/6a90771fe16d749e8fc9268bhttps://doi.org/10.1161/circulationaha.119.044467
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Coronary atherosclerosis in middle‐aged athletes: Current insights, burning questions, and future perspectives2020 · 21 citations
  2. 2Coronary Artery Disease in Athletes-Insights from Cardiac CT2025 · 1 citations
  3. 3Coronary Atherosclerosis in Master Athletes: Current Knowledge and Future Challenges2026
  4. 4Coronary Artery Disease in Male Athletes—Is Sport Healthy in the Long Run?2026
  5. 5Coronary Plaque in Athletes2024 · 3 citations