Why the study?
Does the duration of diabetes mellitus affect the width of the basement membrane of small vessels in young patients compared to non-diabetic controls?
Does the duration of diabetes mellitus affect the width of the basement membrane of small vessels in young patients compared to non-diabetic controls?
The width of the basement membrane of small vessels increases with the duration of diabetes mellitus rather than age in young patients.
Suggests diabetes duration drives microvascular basement membrane changes in youth; hypothesis-generating and leaves prognostic links open.
Measurement shows that the basement membrane of small vessels from nine diabetic patients and eight non‐diabetic patients aged 9–20 years, is larger in the diabetic patient and that the membrane widens with increased duration of diabetes mellitus rather than the aging of the patient.
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M. J. Campbell (1974) studied this question.
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