October 1, 1940Experimental Biology and Medicine

Immunological Studies on Intestinal Theiler's Virus, and Its Relation to Poliomyelitic Virus.

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Population

rhesus monkeys and mice

Design

Preclinical

Follow-up

24 hours

Authors

POPeter K. OlitskyInstitute for Medical Research

Discussion

Member takes

Implication

Distinguishes Theiler's from poliomyelitis virus in primate models; leaves open human disease relevance.

Structured PICO

Population

rhesus monkeys and mice

Intervention

intracerebral inoculation of Theiler's virus and poliomyelitic virus (MV and Philadelphia strains)

Outcome

transmission of virus and production of serum-neutralizing antibodiessurrogate

Theiler's virus is distinct from human poliomyelitis virus, as demonstrated by lack of transmission in monkeys and absence of immunological cross-reactivity.

Cite This Study

Peter K. Olitsky (1940) studied this question.

synapsesocial.com/papers/6a907b2ff009383eee842a0f https://doi.org/10.3181/00379727-45-11675

View Full Paper

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Bookmark

Immunological Studies on Intestinal Theiler's Virus, and Its Relation to Poliomyelitic Virus.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Immunological Studies on Intestinal Theiler's Virus, and Its Relation to Poliomyelitic Virus.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider