This case report highlights the potential role of planned splenectomy and intensive chemotherapy for metastatic angiosarcoma of the spleen.
Remains hypothesis-generating for splenectomy plus chemotherapy in metastatic splenic angiosarcoma; larger prospective trials required before clinical adoption.
We report a case of a 28-year-old man with angiosarcoma of the spleen and liver metastases. The aim of this paper is to underline the importance of planned splenectomy in these patients even if they have metastatic disease, and to propose an intensive chemotherapy regimen consisting of anthracyclines, ifosfamide and mesna with G-CSF support.
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Rupolo et al. (2001) studied this question.
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