Why the study?
Does maximal lung inflation improve specific airway conductance in subjects with varying degrees of methacholine responsiveness?
Population
19 subjects (10 nonreactive and 9 reactive based on FEV1 decrement during graded methacholine challenge)
Comparison
Maximal inspiration to total lung capacity after… vs Pre-inflation values (after methacholine dose)
Design
Other
Follow-up
60 seconds
Authors
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Lung inflation transiently reverses methacholine-induced bronchoconstriction, with the effect decaying nonlinearly over 60 seconds.
Does maximal lung inflation improve specific airway conductance in subjects with varying degrees of methacholine responsiveness?
Lung inflation transiently reverses methacholine-induced bronchoconstriction, with the effect decaying nonlinearly over 60 seconds.
Parham et al. (1983) studied this question.
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